The FDA regulates prescription drug advertising to ensure it is not false or misleading, requires fair balance between benefits and risks, and mandates disclosure of important safety information (established under the Federal Food, Drug, and Cosmetic Act).

The CCPA (2018) grants California consumers broad rights over their personal data, including the right to know, the right to delete, and the right to opt-out of the sale of their personal information, influencing data privacy standards nationwide. (Note: Evolved into CPRA, but CCPA is its foundation).

The FTC's Endorsement Guides require that endorsements and testimonials in advertising be truthful and not misleading, and that material connections between endorsers and advertisers be disclosed, impacting influencer marketing and social media campaigns. (Updated periodically). It applies to social media as well as traditional ads and marketing materials in the US. These laws regulate how pharma can engage with customers via social media and websites, particularly with respect to off-label drug use discussions and reporting of adverse effects from drugs and devices. In this landscape, marketers must monitor digital content and comply with disclosure requirements.